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  5. Esther Lederberg

Births on December 18

Esther Lederberg
1922Dec, 18

Esther Lederberg

Esther Lederberg, American microbiologist (d. 2006)
Esther Miriam Zimmer Lederberg (December 18, 1922 – November 11, 2006) was an American microbiologist and a pioneer of bacterial genetics. She discovered the bacterial virus λ and the bacterial fertility factor F, devised the first implementation of replica plating, and furthered the understanding of the transfer of genes between bacteria by specialized transduction.

Lederberg also founded and directed the now-defunct Plasmid Reference Center at Stanford University, where she maintained, named, and distributed plasmids of many types, including those coding for antibiotic resistance, heavy metal resistance, virulence, conjugation, colicins, transposons, and other unknown factors.

As a woman in a male-dominated field and the wife of Nobel laureate Joshua Lederberg, Esther Lederberg struggled for professional recognition. Despite her foundational discoveries in the field of microbiology, she was never offered a tenured position at a university. Textbooks often ignore her work and attribute her accomplishments to her husband.

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Events on 1922

  • 11Jan

    Diabetes mellitus

    First use of insulin to treat diabetes in a human patient.
  • 2Feb

    James Joyce

    Ulysses by James Joyce is published.
  • 13Sep

    Great Fire of Smyrna

    The final act of the Greco-Turkish War, the Great Fire of Smyrna, commences.
  • 4Nov

    Tutankhamun

    In Egypt, British archaeologist Howard Carter and his men find the entrance to Tutankhamun's tomb in the Valley of the Kings.
  • 24Nov

    Executions during the Irish Civil War

    Nine Irish Republican Army members are executed by an Irish Free State firing squad. Among them is author Robert Erskine Childers, who had been arrested for illegally carrying a revolver.

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