Christine of Saxony, German noblewoman (d. 1549)
Christine of Saxony (25 December 1505 – 15 April 1549) was a German noble, landgravine consort of Hesse by marriage to Philip I, Landgrave of Hesse. She was the regent of Hesse during the absence of her spouse in 1547–1549.

She was the daughter of George the Bearded, Duke of Saxony and Barbara Jagiellon. On 11 December 1523 in Kassel, she married Landgrave Philip I, Landgrave of Hesse. The marriage was arranged to forge an alliance between Hesse and Saxony and was unhappy; Philip claimed to be disgusted by her and only shared her bed by duty. They had ten children.

Whilst married to Christine, Philip practised bigamy and had another nine children with his other (morganatic) wife, Margarethe von der Saale; in 1540, Christine gave her consent to her husband's bigamy with his lover because of her view upon him as her sovereign. Margarethe von der Saale, however, was never seen at court.

During Philip's absence and captivity during 1547–1549, Christine was regent jointly with her oldest son. She died before Philip's release in 1552.