Helena Palaiologina, Queen of Cyprus (d. 1458)
Helena Palaiologina (Greek: Ἑλένη Παλαιολογίνα; 3 February 1428 – 11 April 1458) was a Byzantine princess of the Palaiologos family, who became the Queen consort of Cyprus and Armenia, titular Queen consort of Jerusalem, and Princess of Antioch through her marriage to King John II of Cyprus and Armenia. She was the mother of Queen Charlotte of Cyprus.

She may have poisoned her son-in-law John of Portugal, and ordered the nose of her husband's mistress to be cut off. She did, however, welcome and assist many Byzantine refugees in Cyprus after the Fall of Constantinople in 1453.