The Distomo massacre (Greek: ; German: Massaker von Distomo or Distomo-Massaker) was a Nazi war crime perpetrated by members of the Waffen-SS in the village of Distomo, Greece, in 1944, during the German occupation of Greece during World War II.

"Distomo" may also refer to a work by Federico García LorcaDistomo (Greek: Δίστομο) is a town in western Boeotia, Greece. Since the 2011 local government reform it is part of the municipality Distomo-Arachova-Antikyra, of which it is the seat and a municipal unit. The municipal unit has an area of 131.270 km2, the community 80.498 km2. Population 3,881 (2011). Distomo is situated in the western foothills of Mount Helicon, at about 450 m elevation. It is 5 km north of the Gulf of Corinth coast, 9 km southeast of Arachova, 12 km east of Desfina, 16 km southeast of Delphi, 18 km west of Livadeia and 105 km northwest of Athens. The Greek National Road 48 (Naupactus - Arachova - Livadeia) passes north of the town.

Distomo is known as the site of the Distomo massacre that was perpetrated by the German army against the local inhabitants during the Second World War.

One of the most important monuments of Byzantine architecture and a UNESCO world heritage site, the monastery of Hosios Loukas is situated close to Distomo.

During the ancient Greek times there was a settlement called Amvryssos (Amvrossos) part of which is buried under Distomo. There is an archaeological museum in Distomo officially called Distomo Archaeological Collection (Wikipidia) with a fine exhibit of ancient pottery and artifacts. The local football/soccer team is also named Amvrysseas after the ancient Greek city.

Aluminium of Greece has its production facilities in the coastal village Agios Nikolaos. Other industries include agriculture and services.