The Marcomannic Wars (Latin: bellum Germanicum et Sarmaticum, "German and Sarmatian War") were a series of wars lasting from about 166 AD until 180. These wars pitted the Roman Empire against, principally, the Germanic Marcomanni and Quadi and the Sarmatian Iazyges; there were related conflicts with several other Germanic, Sarmatian and Gothic peoples along both sides of the whole length of the Roman Empire's northeastern European border, the river Danube.

The struggle against the Germans and Sarmatians occupied the major part of the reign of Roman emperor Marcus Aurelius, and it was during his campaigns against them that he started writing his philosophical work Meditations.