James F. Byrnes, American stenographer and politician, 49th United States Secretary of State (d. 1972)
James Francis Byrnes (US: BURNZ; May 2, 1882 – April 9, 1972) was an American judge and politician from South Carolina. A member of the Democratic Party, he served in Congress, on the U.S. Supreme Court, as well as in the executive branch, most prominently as the 49th U.S. Secretary of State under President Harry S. Truman. Byrnes was also the 104th Governor of South Carolina, making him one of the very few politicians to have served in the highest levels of all three branches of the American federal government while also being active in state government.

Born and raised in Charleston, South Carolina, Byrnes pursued a legal career with the help of his cousin, Governor Miles Benjamin McSweeney. Byrnes won election to the U.S. House of Representatives and served from 1911 to 1925. He became a close ally of President Woodrow Wilson and a protégé of Senator Benjamin Tillman. He sought election to the U.S. Senate in 1924, but narrowly lost a runoff election to Coleman Livingston Blease, who had the backing of the Ku Klux Klan. Byrnes then moved his law practice to Spartanburg, South Carolina and prepared for a political comeback. He narrowly defeated Blease in the 1930 Democratic primary and joined the Senate in 1931.

Historian George E. Mowry called Byrnes "the most influential Southern member of Congress between John Calhoun and Lyndon Johnson." In the Senate, Byrnes supported the policies of his longtime friend, President Franklin D. Roosevelt. Byrnes championed the New Deal and sought federal investment in South Carolina water projects. He also supported Roosevelt's foreign policy, calling for a hard line against the Empire of Japan and Nazi Germany. He also opposed some of the labor laws proposed by Roosevelt, such as the Fair Labor Standards Act, which established a minimum wage that hurt his state's competitive advantage of very low factory wages. Roosevelt appointed Byrnes to the Supreme Court in 1941 but asked him to join the executive branch after America's entry into World War II. During the war, Byrnes led the Office of Economic Stabilization and the Office of War Mobilization. He was a candidate to replace Henry A. Wallace as Roosevelt's running mate in the 1944 election, but instead Harry S. Truman was nominated by the 1944 Democratic National Convention.

After Roosevelt's death, Byrnes served as a close adviser to Truman and became U.S. Secretary of State in July 1945. In that capacity, Byrnes attended the Potsdam Conference and the Paris Conference. However, relations between Byrnes and Truman soured, and Byrnes resigned from the Cabinet in January 1947. He returned to elective politics in 1950 by winning election as the governor of South Carolina.

As governor, he opposed the Supreme Court decision in Brown v. Board of Education and sought to establish "separate but equal" as a realistic alternative to the desegregation of schools. Though he remained a Democrat himself, he endorsed most Republican presidential nominees after 1948 and supported Strom Thurmond's switch to the Republican Party in 1964.