James Hamilton, 4th Duke of Hamilton, Scottish general and politician, Lord Lieutenant of Lancashire (b. 1658)
Lieutenant General James Hamilton, 4th Duke of Hamilton and 1st Duke of Brandon (11 April 1658 – 15 November 1712) was a

Scottish nobleman, the Premier Peer of Scotland, and Keeper of the Palace of Holyroodhouse. He was a Master of the Great Wardrobe, Master-General of the Ordnance, Ambassador, and Colonel-in-Chief of his regiment. Hamilton was a major investor in the failed Darien Scheme, which cost many of Scotland's ruling class their fortunes, and he played a leading role in the events leading up to the Act of Union in 1707. He died on 15 November 1712 as the result of a celebrated duel in Hyde Park, Westminster, with Charles Mohun, 4th Baron Mohun, over a disputed inheritance.